Neglected Tropical Diseases and Conditions of the Nervous System

Neglected Tropical Diseases and Conditions of the Nervous System


A number of diseases and conditions that occur primarily in remote rural or poor urban areas of low-income countries have traditionally been neglected by the neuroscience research community. These diseases and conditions affect the nervous system directly (sometimes with lethal consequences) and/or are associated with severe neurological sequels such as epilepsy, cognitive deficits, and sleep disruption. Several diseases also have the effect of promoting poverty by leaving sufferers unable to lead economically productive lives due to cognitive and behavioral disturbances or severe stigmatization. The pathogenesis of neural dysfunction in the diseases addressed in this book and their sequels remains unclear. Neuroscience of Neglected Diseases and Conditions makes available much needed information about how these diseases affect the human nervous system as well as to promote interest in further research. Further research into neglected diseases and conditions will uncover information that sheds light on more general topics of interest to the neuroscience research community.?

Table of contents

Front Matter....Pages i-viii
Front Matter....Pages 1-1
Overview of Neglected Tropical Diseases and Conditions of the Nervous System: Past, Present and Perspectives....Pages 3-19
Travel, Migration and Neglected Tropical Diseases....Pages 21-43
Stigma in Neurological Diseases in the Tropics....Pages 45-63
Front Matter....Pages 65-65
Nematode Infections: Neurological Involvement and Neurobiology....Pages 67-92
Amoebiasis: Neurological Involvement and Neurobiology....Pages 93-110
Neuroschistosomiasis....Pages 111-126
Neurocysticercosis: Neurology and Neurobiology....Pages 127-146
Onchocerciasis: Neurological Involvement....Pages 147-164
Human African Trypanosomiasis: A Highly Neglected Neurological Disease....Pages 165-181
Neurobiology of African Trypanosomiasis....Pages 183-200
Chagas Disease: Neurology and Neurobiology....Pages 201-215
Neurodegeneration in Leprosy: Insights from Model Systems and Patients....Pages 217-232
Rabies: Neurology....Pages 233-249
Rabies: Neurobiology....Pages 251-267
Japanese Encephalitis and Dengue Virus Infection: Neurology and Neurobiology....Pages 269-290
Front Matter....Pages 291-291
Mental Health Problems Associated with the Use and Abuse of Khat ( Catha edulis )....Pages 293-305
Neurobiology of Khat ( Catha edulis Forsk)....Pages 307-319
Konzo: Neurology of a Permanent and Non-progressive Motor Neuron Disorder Associated with Food (Cassava) Toxicity....Pages 321-333
Food Preservation, Snake Venoms and Stroke in the Tropics....Pages 335-351
Front Matter....Pages 353-353
Infectious Causes of Epilepsy?....Pages 355-367
Front Matter....Pages 353-353
Cognitive Impairment and Behavioural Disturbances Following Malaria or HIV Infection in Childhood....Pages 369-390
Back Matter....Pages 391-401


  • Author: Marina Bentivoglio, Esper A. Cavalheiro, Krister Kristensson, Nilesh B. Patel (eds.)
  • Edition: 1
  • Publication Date: 2014
  • Publisher: Springer-Verlag New York
  • ISBN-13: 9781461480990, 9781461481003
  • Pages: 394
  • Format: pdf
  • Size: 8.6M
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