20 Years of Computational Neuroscience

20 Years of Computational Neuroscience


When funding agencies and policy organizations consider the role of modeling and simulation in modern biology, the question is often posed, what has been accomplished ? This book will be organized around a symposium on the 20 year history of the CNS meetings, to be held as part of CNS 2010 in San Antonio Texas in July 2010. The book, like the symposium is intended to summarize progress made in Computational Neuroscience over the last 20 years while also considering current challenges in the field. As described in the table of contents, the chapters authors have been selected to provide wide coverage of the applications of computational techniques to a broad range of questions and model systems in neuroscience. The proposed book will include several features that establish the history of the field. For each article, its author will select an article originally appearing in a CNS conference proceedings from 15 20 years ago. These short (less than 6 page) articles will provide illustrations of the state of the field 20 years ago. The new articles will describe what has been learned about the subject in the following 20 years, and pose specific challenges for the next 20 years. The second historical mechanism will be the reproduction of the first 12 years of posters from the CNS meeting. These posters in and of themselves have become famous in the field (they hang in the halls of the NIH in Bethesda Maryland) and were constructed as allegories for the state and development of computational neuroscience. The posters were designed by the books editor, who will, for the first time, provide a written description of each poster.

Table of contents

Front Matter....Pages i-xiv
Introduction: Origins and History of the CNS Meetings....Pages 1-12
A Pictorial History of the Early Days of Computational Neuroscience: The CNS Meeting Posters....Pages 13-32
History of Neural Simulation Software....Pages 33-71
Learning from the Past: Approaches for Reproducibility in Computational Neuroscience....Pages 73-102
The Emergence of Community Models in Computational Neuroscience: The 40-Year History of the Cerebellar Purkinje Cell....Pages 103-140
Calcium: The Answer to Life, the Universe, and Everything....Pages 141-158
The More We Look, the More Biological Variation We See: How Has and Should This Influence Modeling of Small Networks?....Pages 159-166
20 Years of Noise: Contributions of Computational Neuroscience to the Exploration of the Effect of Background Activity on Central Neurons....Pages 167-186
Still Looking for the Memories: Molecules and Synaptic Plasticity....Pages 187-205
20 Years of the Dynamics of Memory: The Long and Winding Road Linking Cellular Mechanisms to Behavior....Pages 207-227
Spatiotemporal Coding in the Olfactory System....Pages 229-242
20 Years of Learning About Vision: Questions Answered, Questions Unanswered, and Questions Not Yet Asked....Pages 243-270
Reinforcement Learning Models Then-and-Now: From Single Cells to Modern Neuroimaging....Pages 271-277
Back Matter....Pages 279-283


  • Author: John Miller, James M. Bower (auth.), James M Bower (eds.)
  • Edition: 1
  • Publication Date: 2013
  • Publisher: Springer-Verlag New York
  • ISBN-13: 9781461414230, 9781461414247
  • Pages: 294
  • Format: pdf
  • Size: 8.0M
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